Naomi Brewer, Karen Bartholomew, Jane Grant, Anna Maxwell, Georgina McPherson, Helen Wihongi, Collette Bromhead, Nina Scott, Sue Crengle, Sunia Foliaki, Chris Cunningham, Jeroen Douwes, John D Potter
- What it found
- Never-screened and markedly under-screened Maori, Pacific and Asian women aged 30 to 69 were randomised to take an HPV self-sample at their clinic, to be mailed a kit to use at home, or to usual care by cytology. Participation was highest in the mailed-to-home group: 14.6% of Maori women against 2.0% under usual care. Adjusted for study group, screening history, deprivation and age, Maori women sent a kit were 9.7 times more likely to be screened than those offered usual care (95% CI 3.0 to 31.5), Pacific women 6.0 times and Asian women 5.1 times. Of those who self-sampled, 7.9% tested positive for a high-risk HPV type, and clinically appropriate follow-up was completed for 92% of them, needing a mean of 2.5 hours of nurse time each.
- How it was done
- open-label three-arm randomised community trial, 3,553 women, with a non-randomised follow-on substudy
- Why it matters
- It shows the route that actually reaches the women the screening programme has never reached, and it puts a number on the follow-up workforce that route requires.
- What it does not settle
- The authors note they could not tell whether non-responders ever received the invitation, so participation may be underestimated; recruitment was limited to two Auckland districts, so the findings may not carry to rural areas; and participants and staff could not be blinded.